Projects & Focus Areas

Where scientific challenges meet consortium architecture, innovation and impact.

Eagle Synergy Network develops and contributes to multidisciplinary Horizon Europe initiatives across health, climate and environment, bioeconomy, digital technologies and security. Our role varies by project—from consortium architecture and partner development to innovation management, exploitation, stakeholder ecosystems, knowledge valorisation and sustainability.

Below are selected consortium initiatives that illustrate the scientific domains and project roles in which ESN operates.

Health & Life Sciences

  • Digital Twins | New Approach Methodologies (NAMs) | Medical Devices

    DT-TRUST is a Horizon Europe consortium initiative developing a human-anchored New Approach Methodology (NAM) for the testing and validation of high-risk implantable medical devices. The project integrates human biological models, clinical data and in-silico clinical trials to reduce reliance on animal testing while advancing regulatory-ready evidence generation for medical device development.

    ESN ROLE
    Consortium Architect & Beneficiary Partner

    ESN contributes to consortium architecture and proposal integration while participating as a beneficiary in the proposed project, with responsibilities supporting innovation and exploitation, stakeholder engagement, knowledge valorisation, project sustainability and cross-consortium coordination.

  • Health | Medical Devices | Rare Diseases

    A Horizon Europe consortium initiative for the clinical and regulatory development of a novel implantable negative-pressure ventilation system addressing unmet needs in neuromuscular and respiratory disorders.

    ESN ROLE
    Consortium Architecture · Clinical & Technology Partner Development · Regulatory Pathway Integration · Proposal Strategy

    “Towards CE Marking of ORBIS: A Novel Negative-Pressure Ventilation System for Unmet Orphan Needs”

  • EU Cancer Mission | Digital Health

    A mission-driven consortium initiative supporting the European Cancer Patient Digital Centre through integrated digital solutions for patient engagement, data access and healthcare delivery.

    ESN ROLE
    Concept Development · Consortium Architecture · Partner Ecosystem · Proposal Strategy

    HORIZON-MISS-2024-CANCER-01-06

  • Israel Innovation Authority
    As part of the Israel Generic Biochip Technology Consortium (IGBTC), this project focuses on the research and development of biochip technology, driving the bio-convergence industry where engineering and life science intersect. These technologies are poised to transform Israeli industry and have global applications in diagnostics and personalized medicine.

  • HORIZON-HLTH-2024-DISEASE-03-13
    This project validates fluid-derived biomarkers for the prediction and prevention of brain disorders, with a focus on autism spectrum disorder (ASD). Through continuous monitoring using wearable sensors across social, behavioral, cognitive, and physiological domains in natural environments, CONTINEAR-ASD aims to enhance daily functioning, personalize treatment, and reduce the burden of ASD.

  • HORIZON-HLTH-2024-DISEASE-03-14
    A project aimed at tackling high-burden, under-researched medical conditions, MAPS-PTSD applies multimodal analytics to stratify and characterize post-traumatic stress disorder (PTSD), facilitating improved understanding and treatment for affected individuals.

  • HORIZON-HLTH-2024-STAYHLTH-01-05. An innovative solution that uses artificial intelligence, digital twins, and multi source data to create personalized digital tools for stroke prevention. PASSIONATE empowers healthcare providers with predictive analytics, offering tailored strategies to prevent strokes before they occur.

Climate, Environment & Bioeconomy

  • Groundwater Biodiversity | Environmental Monitoring | Digital Innovation

    AQUIFER PULSE is a Horizon Europe consortium initiative developing an integrated framework to assess the presence, functions and sensitivity of groundwater ecosystems. The project combines in-situ biological monitoring, eDNA/eRNA and functional analysis, Earth Observation and environmental data within an integrated digital framework to advance understanding of groundwater ecosystem health and support evidence-based monitoring and management.

    ESN ROLE
    Consortium Architect & Beneficiary Partner

    ESN originated and architects the consortium through concept development, project design, partner ecosystem building and proposal integration. As a proposed beneficiary,

    ESN also contributes to the project's innovation and exploitation strategy, stakeholder ecosystem development, knowledge valorisation, uptake and long-term sustainability, connecting scientific results with pathways toward adoption and impact.

    STATUS
    Horizon Europe Consortium in DevelopmentItem description

  • HORIZON-CL5-2024-D3-02-08. A climate, energy, and mobility project. The SUSTOWINDS project addresses the critical need for sustainable and economical offshore wind farm development, responding to fragmented existing tools that fail to comprehensively integrate ecological, hydrodynamic, noise, and socio-economic factors. This gap leads to inefficient permitting processes, stakeholder conflicts, and inadequate biodiversity protection. SUSTOWINDS offers an innovative, flexible, and modular decision-support platform that consolidates all necessary inputs for robust lifecycle assessments, enabling comprehensive evaluations of environmental impacts while optimizing socio-economic benefits.

  • HORIZON-CL6-2024-FARM2FORK-01-9. This project explores the development of fermented plant-based proteins as innovative dairy replacements, addressing sustainability and health concerns associated with traditional dairy farming.

Civil Security

  • HORIZON-CL3-2024-FCT-01
    This project is developing an integrated generative AI tool to prevent and identify criminal activity on the dark web and instant messaging platforms across the European Union. CRIMIDARK leverages advanced intelligence to fight cybercrime and protect public safety by disrupting organized crime networks.

Digital, Industry, and Innovation

  • VIBE

    Knowledge Valorisation | Digital, Industry & Space

    Valorisation through Intelligent Bridging with Europe (VIBE) was developed as a Horizon Europe CSA addressing Europe's innovation paradox—the gap between excellent research and real-world uptake. The concept combines AI-enabled tools, knowledge valorisation and ecosystem development to strengthen pathways from research to societal, policy and economic impact.

    ESN ROLE
    Consortium Architecture · Knowledge Valorisation Strategy · Innovation Ecosystem Development · Sustainability & Exploitation.

  • Focused on developing advanced radiation detection technologies for image sensors with 3D stacking, RADIS3D aims to improve the precision of radiation detection for various applications, including medical imaging and environmental monitoring.